September 4
| 14:00- | Registration |
|---|---|
| 16:45-17:00 | Opening Address |
| 17:00-18:00 | Keynote Lecture Tadhg P. Begley (Texas A&M University) Prospecting for new flavoenzymes |
| 18:00-20:00 | Welcome Reception & Dinner |
September 5
| 09:00-10:30 | Plenary Session 1 Enzymes in the production of useful chemicals Marko D. Mihovilovic (Vienna University of Technology) Flavoenzyme biocatalysis – Challenges and opportunities Hans Iding (F. Hoffmann-La Roche Ltd.) Ketoreductases and transaminases in pharmaceutical syntheses Alexander Gabibov (Russian Academy of Sciences) Modern pharmacology: Magic bullet & combinatorial approaches. |
|---|---|
| 10:30-11:00 | Coffee Break |
| 11:00-11:30 | Plenary Session 2 Novel technologies using enzymes and cofactors Gavin Williams (North Carolina State University) Synthetic biology approach for the biosynthesis and diversification of natural products |
| 11:30-12:00 | Break |
| 12:00-12:50 | Luncheon Seminar 1 Sponsored by Amano Enzyme Inc. |
| 12:50-13:00 | Break |
| 13:00-15:00 | ERATO Asano Active Enzyme Molecule Project Progress Report Yasuhisa Asano (Biotechnology Research Center and Department of Biotechnology, Toyama Prefectural University) Introduction to the ERATO Session Takuya Yamaguchi and Mohammad Dadashipour (Bioresource Exploration Group, Asano Active Enzyme Molecule Project, ERATO, JST) Exploration of novel biocatalysts from plants and arthropods Kazunori Yamamoto (Bioorganic Chemistry Group, Asano Active Enzyme Molecule Project, ERATO, JST) Development of new enzymatic methods for efficient production of useful chemicals Fumihiro Motojima and Shogo Nakano (Structure and Bioinformatics Research, Asano Active Enzyme Molecule Project, ERATO, JST) Structure and bioinformatics analysis of industrially-promising enzymes for protein engineering Daisuke Matsui (Enzyme Engineering Group, Asano Active Enzyme Molecule Project, ERATO, JST) Exploration of new methods to assign aggregation hot-spots focused on secondary structure and amino acid hydrophobicity |
| 15:00-15:20 | Coffee Break |
| 15:20-17:20 | Plenary Session 3 Medical, pharmaceutical and nutritional applications of cofactors and enzymes Joelle Pelletier (University of Montreal) The ins and outs of bacterial cytochrome P450 monooxygenases Kiyoshi Fukui (Tokushima University) Medical aspects and chiral science of amino acid metabolism: regulation of human D-amino acid oxidase gene expression and implication for translation to neuropsychiatric disorders Takashi Nakagawa (University of Toyama) Role of NAD metabolism in disease En-Pei Chiang (National Chung Hsing University) Regulation of folate-mediated one-carbon metabolic kinetics by genetic variations |
| 17:30-19:00 | Poster Session 1 |
September 6
| 09:00-10:30 | Plenary Session 4 Structure, function and catalytic mechanisms of enzymes and cofactors Pimchai Chaiyen (Mahidol University) Mechanism and biocatalysis of two-component flavin-dependent monooxygenases Robert S. Phillips (University of Georgia) Ground-state destabilization in pyridoxal-5’-phosphate dependent enzymes: Tyrosine phenol-lyase and tryptophan indole-lyase Pablo Sobrado (Virginia Polytechnic Institute and State University) Noncanonical reactions catalyzed by atypical flavoenzymes |
|---|---|
| 10:30-11:00 | Coffee Break |
| 11:00-12:00 | Plenary Session 5 Molecular biology and biosynthetic aspects of cofactors Michael Richter (Fraunhofer Institute for Interfacial Engineering and Biotechnology) Functional diversity of organic enzyme cofactors Koji Sode (Tokyo University of Agriculture and Technology) Investigation of the cofactors and electron transfer pathway of FAD dependent dehydrogenase complexes capable of direct electron transfer |
| 12:00-13:00 | Lunch Break |
| 13:00-18:30 | Excursion |
| 19:00-21:00 | Banquet at Hotel Aqua Kurobe |
September 7
| 09:00-11:40 | Oral Session OA01-08 | Oral Session OB01-08 |
|---|---|---|
| 11:40-12:00 | Break | |
| 12:00-12:50 | Luncheon Seminar 2 Sponsored by Japanese Coenzyme Q Association | |
| 12:50-13:00 | Break | |
| 13:00-15:40 | Oral Session OA09-16 | Oral Session OB09-16 |
| 15:40-16:00 | Coffee Break | |
| 16:00-17:30 | Plenary Session 6 Exploration of enzymatic activities by screening and protein engineering Ulf Hanefeld (Delft University of Technology) Introducing and reducing the nitrile group Paola Laurino (Weizmann Institute of Science in Rehovot) A journey from an ancient finger print of Rossmann fold enzymes to cofactor engineering Uwe Bornscheuer (University of Greifswald) Protein engineering as a tool to improve PLP-dependent enzymes for applications in biocatalysis | |
| 17:40-19:10 | Poster Session 2 | |
September 8
| 09:00-11:40 | Oral Session OA17-24 | Oral Session OB17-24 |
|---|---|---|
| 11:45-12:00 | Closing Ceremony | |
