Final Program
Program at a glance

September 4

16:45-17:00Opening Address
17:00-18:00Keynote Lecture
Tadhg P. Begley (Texas A&M University)
Prospecting for new flavoenzymes
18:00-20:00Welcome Reception & Dinner

September 5

09:00-10:30Plenary Session 1
Enzymes in the production of useful chemicals
Marko D. Mihovilovic (Vienna University of Technology)
Flavoenzyme biocatalysis – Challenges and opportunities
Hans Iding (F. Hoffmann-La Roche Ltd.) 
Ketoreductases and transaminases in pharmaceutical syntheses
Alexander Gabibov (Russian Academy of Sciences) 
Modern pharmacology: Magic bullet & combinatorial approaches.
10:30-11:00Coffee Break
11:00-11:30Plenary Session 2
Novel technologies using enzymes and cofactors
Gavin Williams (North Carolina State University)
Synthetic biology approach for the biosynthesis and diversification of
natural products
12:00-12:50Luncheon Seminar 1 Sponsored by Amano Enzyme Inc.
13:00-15:00ERATO Asano Active Enzyme Molecule Project Progress Report
Yasuhisa Asano (Biotechnology Research Center and Department of Biotechnology, Toyama Prefectural University) 
Introduction to the ERATO Session
Takuya Yamaguchi and Mohammad Dadashipour
(Bioresource Exploration Group, Asano Active Enzyme Molecule Project, ERATO, JST)
Exploration of novel biocatalysts from plants and arthropods
Kazunori Yamamoto
(Bioorganic Chemistry Group, Asano Active Enzyme Molecule Project, ERATO, JST)
Development of new enzymatic methods for efficient production of useful chemicals
Fumihiro Motojima and Shogo Nakano
(Structure and Bioinformatics Research, Asano Active Enzyme Molecule Project, ERATO, JST)
Structure and bioinformatics analysis of industrially-promising enzymes for protein engineering
Daisuke Matsui
(Enzyme Engineering Group, Asano Active Enzyme Molecule Project, ERATO, JST)
Exploration of new methods to assign aggregation hot-spots focused
on secondary structure and amino acid hydrophobicity
15:00-15:20Coffee Break
15:20-17:20Plenary Session 3
Medical, pharmaceutical and nutritional applications of cofactors and enzymes
Joelle Pelletier (University of Montreal)
The ins and outs of bacterial cytochrome P450 monooxygenases
Kiyoshi Fukui (Tokushima University)
Medical aspects and chiral science of amino acid metabolism: regulation of human D-amino acid oxidase gene expression and implication for translation to neuropsychiatric disorders
Takashi Nakagawa (University of Toyama)
Role of NAD metabolism in disease
En-Pei Chiang (National Chung Hsing University)
Regulation of folate-mediated one-carbon metabolic kinetics by
genetic variations
17:30-19:00Poster Session 1

September 6

09:00-10:30Plenary Session 4
Structure, function and catalytic mechanisms of enzymes and cofactors
Pimchai Chaiyen (Mahidol University)
Mechanism and biocatalysis of two-component flavin-dependent monooxygenases
Robert S. Phillips (University of Georgia)
Ground-state destabilization in pyridoxal-5’-phosphate dependent
enzymes: Tyrosine phenol-lyase and tryptophan indole-lyase
Pablo Sobrado (Virginia Polytechnic Institute and State University)
Noncanonical reactions catalyzed by atypical flavoenzymes
10:30-11:00Coffee Break
11:00-12:00Plenary Session 5
Molecular biology and biosynthetic aspects of cofactors
Michael Richter (Fraunhofer Institute for Interfacial Engineering and Biotechnology)
Functional diversity of organic enzyme cofactors
Koji Sode (Tokyo University of Agriculture and Technology)
Investigation of the cofactors and electron transfer pathway of FAD dependent dehydrogenase complexes capable of direct electron transfer
12:00-13:00Lunch Break
19:00-21:00Banquet at Hotel Aqua Kurobe

September 7

09:00-11:40Oral Session
Oral Session
12:00-12:50Luncheon Seminar 2 Sponsored by Japanese Coenzyme Q Association
13:00-15:40Oral Session
Oral Session
15:40-16:00Coffee Break
16:00-17:30Plenary Session 6
Exploration of enzymatic activities by screening and protein engineering
Ulf Hanefeld (Delft University of Technology)
Introducing and reducing the nitrile group
Paola Laurino (Weizmann Institute of Science in Rehovot)
A journey from an ancient finger print of Rossmann fold enzymes to
cofactor engineering
Uwe Bornscheuer (University of Greifswald)
Protein engineering as a tool to improve PLP-dependent enzymes for
applications in biocatalysis
17:40-19:10Poster Session 2

September 8

09:00-11:40Oral Session
Oral Session
11:45-12:00Closing Ceremony